Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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1,096 – 1,110 of 3,715 results

1,096

Medchemexpress LLC N-(2,4-dimethoxyphenyl)-N-(1-oxo-2-propyn-1-yl)-2-(2-thienyl)glycyl-glycine, ethyl ester | 1401089-31-3 | 99.3% | 430.47 g/mol | C21H22N2O6S | 25 MG

PACMA 31 is an irreversible, orally active small-molecule inhibitor of protein disulfide isomerase (PDI) used as a research reagent in biochemical and cellular studies. It covalently modifies active-site cysteines and has shown antitumor activity in preclinical models. For research use only; not for human or clinical applications.

Irreversible inhibitor of protein disulfide isomerase
Forms covalent bond with active-site cysteines
High purity (99.3%) suitable for assays
Molecular weight 430.47 g/mol; formula C21H22N2O6S
Available in 25 MG vial for laboratory use
CAS number 1401089-31-3 for substance identification

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1,097

Ambeed 5Nitroisoindoline1 3dione

5-Nitroisoindoline-1,3-dione, 89-40-7, 97%

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1,098

Ambeed Methyl pyrimidine2carboxylate

Methyl pyrimidine-2-carboxylate, 34253-03-7, 97%

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1,099

Ambeed 4 4 Bipyridine

4,4'-Bipyridine, 553-26-4, 98%

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1,100

Ambeed 4 Ethoxycarbonyl N N Ntrimethy

4-(Ethoxycarbonyl)-N,N,N-trimethylbenzenaminium trifluoromethanesulfonate, 124915-06-6, 95%

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1,101

Apexbio Technology LLC FLI-06 313967-18-9 10mM (in 1mL DMSO)

FLI-06 (CAS 313967-18-9) is a small molecule inhibitor of the Notch signaling pathway exhibiting an EC50 of 2 3 M Notch signaling regulates cell fate decisions and its dysregulation is implicated in oncogenesis and developmental disorders FLI-06 impedes Notch E-eGFP accumulation and reduces NICD-eGFP production in HeLa cells with effects that are fully reversible upon washout indicating low cytotoxicity Additionally FLI-06 significantly decreases A secretion upstream of - and -secretase cleavage events and disrupts Golgi structure by interfering with early secretory pathway membrane trafficking This compound is valuable for studying Notch signaling secretory pathway dynamics and related cellular processes

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1,102

Sigma Aldrich Fine Chemicals Biosciences Aripiprazole >=98% (HPLC) | 129722-12-9 | 50MG

Aripiprazole >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 448.39 | 129722-12-9 | 50MG

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1,103

Medchemexpress LLC DYB-03 | 2982792-85-6 | 99.5% | 479.56 | 1 ML

DYB-03 is an orally active HIF-1α/EZH2 inhibitor. It inhibits the migration, invasion, and angiogenesis of lung cancer cells and HUVECs both in vitro and in vivo. Additionally, DYB-03 induces apoptosis in A549 and H460 cells that are resistant to 2-ME2 and GSK126.

Oral active HIF-1α/EZH2 inhibitor
Inhibits migration, invasion, and angiogenesis of lung cancer cells and HUVECs (in vitro and in vivo)
Induces apoptosis in 2-ME2- and GSK126-resistant A549 and H460 cells

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1,104

Medchemexpress LLC Interleukin-31 (canine) | >95.0% | 20UG

Recombinant canine interleukin-31 expressed in HEK293 mammalian cells and supplied as a lyophilized N-His-tagged protein for research use. The product is provided as a stabilized lyophilized powder formulated in PBS with trehalose, exhibits glycosylation-dependent mobility on SDS-PAGE, and should be stored frozen and handled per supplier recommendations to preserve activity.

Produced in HEK293 mammalian cells for native-like glycosylation.
Contains N-terminal His tag to enable purification and detection.
Lyophilized powder stabilized with trehalose for storage and shipping.
Low endotoxin level (<1 EU/μg) suitable for sensitive assays.
Purity greater than 95% as determined by reducing SDS-PAGE.
Molecular weight approximately 26-36 kDa due to glycosylation.
Reconstitute and store according to supplier recommendations to preserve activity.
For research use only; not for clinical or diagnostic applications.

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1,105

Apexbio Technology LLC Batimastat (BB-94)(Synonyms: BB-94, Batimastat, MMP inhibitor BB-94), 10mg, CAS: 130370-60-4.

Batimastat (BB-94 CAS 130370-60-4) is a synthetic small-molecule inhibitor targeting matrix metalloproteinases (MMPs) Structurally a polypeptide-like analogue of collagen substrates batimastat contains a peptidic backbone and a hydroxamate moiety that binds the catalytic zinc atom of MMPs It inhibits several MMP subtypes markedly including MMP-1 MMP-2 MMP-3 MMP-7 and MMP-9 with reported IC50 values of 3 4 20 6 and 4 nM respectively In preclinical studies batimastat demonstrates inhibitory effects on tumor growth and angiogenesis across various tumor models including ovarian and colon carcinoma xenografts making it relevant for cancer research and therapeutic development

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1,106

TARGETMOL CHEMICALS INC THZ1 2HCL 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. THZ1 2HCl (THZ1 Dihydrochloride) is a selective covalent and allosteric inhibitor of CDK7 with an IC50 of 3.2 nM. THZ1 2HCl has antiproliferative effects on a variety of cancer cell lines. purity: 98%

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1,107

Medchemexpress LLC 1,7-Heptanediamine | 646-19-5 | 98.54% | 130.23 | 10 G

1,7-Heptanediamine (C7) is a deoxyhypusine synthase inhibitor with an IC50 value of 4.5 μM. It appears as a solid below 26°C and a liquid above 29°C, with a colorless to off-white appearance. It is soluble in water at ≥ 100 mg/mL (767.87 mM).

Deoxyhypusine synthase inhibitor with an IC50 value of 4.5 μM
Appears as a solid below 26°C and a liquid above 29°C
Colorless to off-white appearance
Soluble in water at ≥ 100 mg/mL

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1,108

Ambeed Palladium II acetate

Palladium(II) acetate, 3375-31-3, 99.9%

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1,109

Ambeed R 2Amino3 4fluorophenyl propa

(R)-2-Amino-3-(4-fluorophenyl)propanoic acid, 18125-46-7, 98%

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1,110

Medchemexpress LLC 6-(2-(4-((4-fluorophenyl)phenylmethylidene)piperidin-1-yl)ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one | 93076-89-2 | MFCD00055114 | ≥98.0% | 459.58 g/mol | C27H26FN3OS | 25 MG

R 59-022 is a small-molecule research reagent that inhibits diacylglycerol kinase (DGK) and functions as a 5-HT receptor antagonist. It is used to modulate protein kinase C (PKC) activation and diacylglycerol-dependent signaling in biochemical and cell-based studies. Chemical identifiers include CAS 93076-89-2, formula C27H26FN3OS, and molecular weight ≈459.58 g/mol.

Potent DGK inhibitor (reported IC50 ≈ 2.8 μM).
Modulates PKC activation and diacylglycerol signaling.
Used in platelet aggregation and cellular signaling studies.
High reported purity (≥98%).
Provided in small research quantities suitable for assay development.

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Quinolines and derivatives

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Medchemexpress LLC N-(2,4-dimethoxyphenyl)-N-(1-oxo-2-propyn-1-yl)-2-(2-thienyl)glycyl-glycine, ethyl ester | 1401089-31-3 | 99.3% | 430.47 g/mol | C21H22N2O6S | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC FLI-06 313967-18-9 10mM (in 1mL DMSO) Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC DYB-03 | 2982792-85-6 | 99.5% | 479.56 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Interleukin-31 (canine) | >95.0% | 20UG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Batimastat (BB-94)(Synonyms: BB-94, Batimastat, MMP inhibitor BB-94), 10mg, CAS: 130370-60-4. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

TARGETMOL CHEMICALS INC THZ1 2HCL 5MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1,7-Heptanediamine | 646-19-5 | 98.54% | 130.23 | 10 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More